{
 "version": "https://jsonfeed.org/version/1.1",
 "title": "WAKENEX — Human OS: latest",
 "home_page_url": "https://wakenex.com/topics/health/",
 "feed_url": "https://wakenex.com/topics/health/latest.json",
 "description": "Each week's new research from the top international journals, read for what it actually shows.",
 "language": "en",
 "items": [
  {
   "id": "38384fb9bc937d38",
   "url": "https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1005140",
   "external_url": "https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1005140",
   "title": "Burden of bacterial antimicrobial resistance associated with modifiable human antibiotic consumption: An observational study",
   "content_text": "by Benjamin J. Singer, Alec Gleason, Isabella Impalli, Mikkel D. Nagorsen, Chungman Chae, Lauren C. Granskog, Philip C. Lee, Ramanan Laxminarayan, Joseph A. Lewnard Background Human antibiotic use is widely believed to…",
   "language": "en",
   "_wakenex": {
    "source": "plos-medicine",
    "source_name": "PLOS Medicine",
    "group": "journals",
    "why_en": "Quantified link between individual antibiotic use and resistance burden sharpens cost-benefit thinking.",
    "why_zh": "个人抗生素使用与耐药负担的量化关联，有助于更清晰地权衡用药决策。",
    "title_zh": "与可改变的人类抗生素消费相关的细菌抗菌素耐药性负担：一项观察性研究",
    "summary_zh": "作者：Benjamin J. Singer、Alec Gleason、Isabella Impalli、Mikkel D. Nagorsen、Chungman Chae、Lauren C. Granskog、Philip C. Lee、Ramanan Laxminarayan、Joseph A. Lewnard 背景：人类抗生素使用被普遍认为……",
    "original_language": "en"
   },
   "date_published": "2026-10-26T14:00:00Z"
  },
  {
   "id": "17b438073d08117a",
   "url": "https://ajcn.nutrition.org/article/S0002-9165(26)00410-7/fulltext?rss=yes",
   "external_url": "https://ajcn.nutrition.org/article/S0002-9165(26)00410-7/fulltext?rss=yes",
   "title": "Impact of minimally processed versus milled whole grains on glycaemic control in type 2 diabetes: A 12-week randomised trial",
   "content_text": "Whole grains are widely promoted within a healthy diet, with dietary advice encouraging the replacement of refined grains with whole grains. However, data from small trials indicates that milling or processing whole…",
   "language": "en",
   "_wakenex": {
    "source": "ajcn",
    "source_name": "The American Journal of Clinical Nutrition",
    "group": "journals",
    "evidence": [
     "rct",
     "RCT",
     "随机对照试验",
     3,
     "auto"
    ],
    "why_en": "Grain processing method affects blood sugar control, not just the whole-grain label.",
    "why_zh": "谷物加工方式影响血糖控制，\"全谷物\"标签本身不足以判断其健康价值。",
    "title_zh": "微加工与碾磨全谷物对2型糖尿病血糖控制的影响：一项为期12周的随机试验",
    "summary_zh": "全谷物在健康饮食中被广泛推广，膳食建议鼓励以全谷物替代精制谷物。然而，来自小型试验的数据表明，碾磨或加工全谷物……",
    "original_language": "en"
   },
   "date_published": "2026-10-26T00:00:00Z"
  },
  {
   "id": "4b0634e56c2d1b5c",
   "url": "https://ajcn.nutrition.org/article/S0002-9165(26)00409-0/fulltext?rss=yes",
   "external_url": "https://ajcn.nutrition.org/article/S0002-9165(26)00409-0/fulltext?rss=yes",
   "title": "Metabolic phenotyping identifies early interindividual variation in infant energy expenditure with implications for obesity risk",
   "content_text": "Pediatric obesity is a major public health crisis. Early identification of metabolic traits that increase individual risk are emerging. As such, identification of variability in early energy expenditure would reveal the…",
   "language": "en",
   "_wakenex": {
    "source": "ajcn",
    "source_name": "The American Journal of Clinical Nutrition",
    "group": "journals",
    "why_en": "Early metabolic variability in infants shows energy expenditure differs before obesity develops.",
    "why_zh": "婴儿期代谢表型差异先于肥胖出现，提示肥胖风险有早期生物学根源。",
    "title_zh": "代谢表型分析识别婴儿能量消耗的早期个体间差异及其对肥胖风险的意义",
    "summary_zh": "儿童肥胖是重大公共卫生危机。能够增加个体风险的代谢特征的早期识别正在不断涌现。因此，识别早期能量消耗的变异性将揭示……",
    "original_language": "en"
   },
   "date_published": "2026-10-26T00:00:00Z"
  },
  {
   "id": "7dd5636f840594c6",
   "url": "https://ajcn.nutrition.org/article/S0002-9165(26)00408-9/fulltext?rss=yes",
   "external_url": "https://ajcn.nutrition.org/article/S0002-9165(26)00408-9/fulltext?rss=yes",
   "title": "Association of ultra-processed food consumption with incident myeloid neoplasms: population-based cohort study",
   "content_text": "Higher ultra-processed food (UPF) consumption has been linked to chronic disease, but prospective evidence for incident myeloid neoplasms remains limited.",
   "language": "en",
   "_wakenex": {
    "source": "ajcn",
    "source_name": "The American Journal of Clinical Nutrition",
    "group": "journals",
    "evidence": [
     "cohort",
     "Cohort",
     "队列研究",
     2,
     "auto"
    ],
    "why_en": "Population cohort links ultra-processed food intake to a distinct cancer category, not just metabolic disease.",
    "why_zh": "队列研究将超加工食品与髓系肿瘤关联，拓宽了UPF危害的认知范围。",
    "title_zh": "超加工食品摄入与新发髓系肿瘤的关联：基于人群的队列研究",
    "summary_zh": "较高的超加工食品（UPF）摄入已被证实与慢性疾病相关，但关于新发髓系肿瘤的前瞻性证据仍然有限。",
    "original_language": "en"
   },
   "date_published": "2026-10-26T00:00:00Z"
  },
  {
   "id": "a0af615c63ffb0f5",
   "url": "https://www.medrxiv.org/content/10.64898/2026.10.22.26366259v1",
   "external_url": "https://www.medrxiv.org/content/10.64898/2026.10.22.26366259v1",
   "title": "Cumulative Prenatal Adversity and Fronto-Limbic White Matter Development Across Adolescence",
   "content_text": "Importance: The prenatal period is a critical window for intergenerational transmission of adversity, yet the neural substrates through which cumulative prenatal stress becomes biologically embedded in offspring brain…",
   "language": "en",
   "_wakenex": {
    "source": "medrxiv-lifestyle",
    "source_name": "medRxiv · lifestyle-related categories",
    "group": "preprints",
    "doi": "10.64898/2026.10.22.26366259",
    "evidence": [
     "cohort",
     "Cohort",
     "队列研究",
     2,
     "auto"
    ],
    "why_en": "Cumulative prenatal stress is biologically embedded in fronto-limbic white matter, shaping adolescent brain development.",
    "why_zh": "产前累积压力通过白质结构变化传递至后代大脑，揭示逆境跨代嵌入的神经基础。",
    "title_zh": "累积产前逆境与青少年期额叶-边缘系统白质发育",
    "summary_zh": "重要性：产前期是逆境代际传递的关键窗口，然而累积产前应激通过何种神经底物在后代大脑中发生生物性嵌入……",
    "original_language": "en"
   },
   "date_published": "2026-10-26T00:00:00Z"
  },
  {
   "id": "1556f8501f0337ff",
   "url": "https://www.medrxiv.org/content/10.64898/2026.10.22.26366260v1",
   "external_url": "https://www.medrxiv.org/content/10.64898/2026.10.22.26366260v1",
   "title": "A Local Enrichment Computational Framework to Identify Disease-Enriched Physical Activity Patterns",
   "content_text": "Wearable accelerometers enable continuous monitoring of physical activity (PA), yet conventional summary measures and population-wide clustering approaches may overlook disease-associated behavioral heterogeneity. Here…",
   "language": "en",
   "_wakenex": {
    "source": "medrxiv-lifestyle",
    "source_name": "medRxiv · lifestyle-related categories",
    "group": "preprints",
    "doi": "10.64898/2026.10.22.26366260",
    "evidence": [
     "cohort",
     "Cohort",
     "队列研究",
     2,
     "auto"
    ],
    "why_en": "Disease-linked activity patterns hide inside individual wearable data that population averages erase.",
    "why_zh": "可穿戴数据的群体平均掩盖个体疾病相关活动模式，提示分析方法选择影响结论。",
    "title_zh": "用于识别疾病富集体力活动模式的局部富集计算框架",
    "summary_zh": "可穿戴加速度计能够实现体力活动（PA）的持续监测，但传统汇总指标和全人群聚类方法可能忽略与疾病相关的行为异质性。本文……",
    "original_language": "en"
   },
   "date_published": "2026-10-26T00:00:00Z"
  },
  {
   "id": "f404e215d326c199",
   "url": "http://news.sciencenet.cn/htmlnews/2026/10/573563.shtm",
   "external_url": "http://news.sciencenet.cn/htmlnews/2026/10/573563.shtm",
   "title": "Petting a dog doesn't relieve stress immediately, but helps the body handle the next stressor",
   "content_text": "Coming home to a tail-wagging, four-legged furry friend can ease the stress built up over the course of a day. Humans have long drawn comfort from petting dogs. A large body of research acknowledges the benefits of pet ownership for well-being, but the mechanisms driving those benefits remain unclear. ...",
   "language": "en",
   "_wakenex": {
    "source": "sciencenet-intl",
    "source_name": "ScienceNet · International news",
    "group": "media-zh",
    "why_en": "Pet contact may buffer future stress responses, not just soothe present ones.",
    "why_zh": "与宠物接触可能增强对下一次压力的缓冲能力，而非仅缓解当下情绪。",
    "title_zh": "抚摸狗不能立刻减压，但能帮身体扛住下一次压力",
    "summary_zh": "回到家中，看到一只摇着尾巴的四条腿毛茸茸朋友，可以缓解一天中积累的压力。自古以来，人类就从抚摸狗中获得慰藉。大量研究承认养宠物对福祉的益处，但驱动这些益处的机制仍不清楚。...",
    "original_language": "zh"
   },
   "date_published": "2026-10-25T10:28:00Z"
  },
  {
   "id": "95a4ab72d2d1427d",
   "url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364102v2",
   "external_url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364102v2",
   "title": "Social and behavioral risk factors are associated with age-related differences in sustained attention: A cross-sectional GradCPT analysis of the All of Us dataset",
   "content_text": "Background Attentional control declines with normal aging, yet the role of modifiable lifestyle factors in accelerating this decline remains incompletely characterised in large, diverse populations. We examined…",
   "language": "en",
   "_wakenex": {
    "source": "medrxiv-lifestyle",
    "source_name": "medRxiv · lifestyle-related categories",
    "group": "preprints",
    "doi": "10.64898/2026.10.01.26364102",
    "evidence": [
     "xs",
     "Cross-sectional",
     "横断面研究",
     1,
     "auto"
    ],
    "why_en": "Modifiable behaviors predict attention decline rate; identifies levers beyond age alone.",
    "why_zh": "可改变的行为习惯影响注意力衰退速度，年龄不是唯一决定因素。",
    "title_zh": "社会与行为风险因素与持续注意力的年龄相关差异存在关联：基于\"All of Us\"数据集的横断面GradCPT分析",
    "summary_zh": "背景 注意力控制随正常老化而下降，然而可改变的生活方式因素在加速这一下降中所起的作用，在大规模多元人群中尚未得到充分描述。我们考察了……",
    "original_language": "en"
   },
   "date_published": "2026-10-24T00:00:00Z"
  },
  {
   "id": "95b874e31edc585a",
   "url": "https://europepmc.org/article/PPR/PPR1349433",
   "external_url": "https://europepmc.org/article/PPR/PPR1349433",
   "title": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis",
   "content_text": "Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder: Systematic Review and Meta-Analysis",
   "language": "en",
   "_wakenex": {
    "source": "europepmc-medrxiv",
    "source_name": "Europe PMC · medRxiv preprints (keyword search)",
    "group": "preprints",
    "doi": "10.64898/2026.10.21.26366048",
    "evidence": [
     "meta",
     "Meta-analysis",
     "荟萃分析",
     4,
     "auto"
    ],
    "why_en": "A meta-analysis adds weight to MBSR as a structured anxiety-management method.",
    "why_zh": "荟萃分析为正念减压作为焦虑管理方法提供了更可靠的证据基础。",
    "title_zh": "正念减压疗法用于广泛性焦虑障碍：系统综述与元分析",
    "summary_zh": "",
    "original_language": "en"
   },
   "date_published": "2026-10-24T00:00:00Z"
  },
  {
   "id": "acc9ec145d02d8ef",
   "url": "http://news.sciencenet.cn/htmlnews/2026/10/573501.shtm",
   "external_url": "http://news.sciencenet.cn/htmlnews/2026/10/573501.shtm",
   "title": "A Quarter of Major Depression Cases May Be Caused by Disruptions to the Body's Biological Clock",
   "content_text": "A study suggests that a quarter of depression cases are caused by disruptions to the body's biological clock. This newly identified \"circadian depression\" responds poorly to standard antidepressants, but may be addressed through melatonin or behavioural strategies (…",
   "language": "en",
   "_wakenex": {
    "source": "sciencenet-intl",
    "source_name": "ScienceNet · International news",
    "group": "media-zh",
    "why_en": "A depression subtype tied to clock disruption responds differently, so circadian history is a relevant diagnostic dimension.",
    "why_zh": "昼夜节律紊乱可能是抑郁的独立亚型，评估睡眠节律有助于理解病情分类。",
    "title_zh": "四分之一的重度抑郁症病例或由人体生物钟失调引起",
    "summary_zh": "一项研究表明，四分之一的抑郁症病例是由人体生物钟失调引起的。这种新发现的“昼夜节律性抑郁症”对标准抗抑郁药反应不佳，但可能通过服用褪黑素或采取行为策略（...",
    "original_language": "zh"
   },
   "date_published": "2026-10-23T17:04:00Z"
  }
 ],
 "_wakenex": {
  "generated_at": "2026-10-27T12:59:19+07:00",
  "note": "Items from public sources that passed WAKENEX's two gates (still useful in a year; the reader can think or do one new thing), linked to the original. The items are not WAKENEX claims; _wakenex.why_en / why_zh is WAKENEX's one-line reading of what each changes."
 }
}